Russian Journal of Clinical Ophthalmology
ISSN 2311-7729 (Print), 2619-1571 (Online)

Activation of uveolymphatic outflow pathway after non-penetrating glaucoma surgery without filtering bleb: case reports

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DOI: 10.32364/2311-7729-2021-21-2-108-115

V. Kumar1,2, K.A. Abu Zaalan1, M.A. Frolov1, A.S. Shradqa2, G.N. Dushina1,2,
A.I. Bezzabotnov2, Z.Sh. Rustamova1

1RUDN University, Moscow, Russian Federation

2LLC Center of Eye Microsurgery “PRO zrenie”, Moscow, Russian Federation

The authors propose a modified technique of non-penetrating filtering glaucoma surgery for primary open-angle glaucoma (POAG) to improve the uveoscleral outflow. The study enrolled 11 patients with POAG. A novel surgical technique included two steps. The first step was modified deep sclerectomy and cyclodyalysis with collagen implant placed into the supraciliary space. The second step (after 7–10 days) was YAG laser trabeculotomy. Surgical site and adjacent areas were examined by optical coherence tomography (OCT). After 6 months, mean IOP significantly reduced by 52% (from 30.0±10.3 mm Hg to 14.6±5.0 mm Hg, р=0.0004) while the number of IOP-lowering medications reduced by 79% (from 2.9±1.0 to 0.6±0.4, р=0.000001). The aqueous humor outflow occurred through conjunctival lymphatic vessels without filtering bleb formation, as illustrated by OCT. Postoperative complications were minor and easy-to-treat. Three case reports are discussed.

Keywords: open-angle glaucoma, glaucoma surgery, conjunctival lymphatics, filtering bleb, non-penetrating glaucoma surgery, uveolymphatic outflow pathway.

For citation: Kumar V., Abu Zaalan K.A., Frolov M.A. et al. Activation of uveolymphatic outflow pathway after non-penetrating glaucoma surgery without filtering bleb: case reports. Russian Journal of Clinical Ophthalmology. 2021;21(2):–115. DOI: 10.32364/2311-7729-2021-21-2-108-115.




About the authors:

1,2Vinod Kumar — Doct. of Sci. (Med.), Professor of the Department of Eye Diseases, ORCID iD 0000-0002-5489-4607;

1Kamal A. Abu Zaalan — postgraduate student of the Department of Eye Diseases, ORCID iD 0000-0001-9542-222X;

1Mikhail A. Frolov — Doct. of Sci. (Med.), Professor, Head of the Department of Eye Diseases, ORCID iD 0000-0002-9833-6236;

2Ahmad S. Shradqa — Cand. of Sci. (Med.), ophthalmologist, ORCID iD 0000-0001-5814-9041;

1,2Galina N. Dushina — Cand. of Sci. (Med.), assistant of the Department of Eye Diseases, Head Doctor, ORCID iD 0000-0002-6243-1012;

2Andrey I. Bezzabotnov — ophthalmologist, ORCID iD 0000-0002-5677-3649;

1Zarina Sh. Rustamova — clinical resident, ORCID iD 0000-0001-7835-0770.

1RUDN University. 6, Miklukho-Maklaya str., Moscow, 117198, Russian Federation.

2LLC Center of Eye Microsurgery “PRO zrenie”. 1, Gorshin str., Moscow Region, Khimki, 141407, Russian Federation.


Contact information: Vinod Kumar, e-mail: kumarvinod1955@gmail.com. Financial Disclosure: no authors have a financial or property interest in any material or method mentioned. There is no conflict of interests. Received 24.03.2021. 



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